Professor Stephen Bloom
Professor Bloom received his undergraduate medical training at Cambridge University. His house officer, senior house officer and registrar posts were largely undertaken at The Middlesex Hospital where he also received his MRC Clinical Research Fellow training. He moved to the Royal Postgraduate Medical School at Hammersmith Hospital in 1974 where his roles have included Senior Lecturer (Consultant Physician), Reader in Medicine, Chairman of the Higher Degrees Committee and Academic Board, Professor of Medicine (Honorary Consultant Physician), Director of the Endocrinology Clinical Service and Deputy Director, Department of Medicine, Director of Chemical Pathology (renamed Metabolic Medicine and later Investigative Medicine), Chief of Clinical Service Chemical Pathology and Chief of Service Endocrinology and Diabetes.
His research work over the years falls into five related categories: Endocrinology clinical research, physiology and pathology of gut hormones, control of insulin release and insulin resistance, role of neuropeptides in organ control and the role of neuropeptides in CNS regulation of appetite and related hypothalamic functions. He currently leads a research group investigating hypothalamic appetite control systems and gut hormones. This group’s discovery that oxyntomodulin reduces appetite offers a potential new treatment for obesity and in 2005 Steve co-founded spin out company ‘Thiakis Ltd’ to commercialise these findings.
In the past Steve has been a member of the Main Scientific Board for AstraZeneca and advisory boards for Upjohn and Novartis. He has published over 1000 papers (excluding review articles) in journals such as Nature, J Biol Chem, PNAS, JCI and NEJM.
He completed his medical training at St Bartholomew's Hospital Medical School, University of London in 1994. During this time he also completed an Intercalated BSc in Biochemistry (awarded First Class Honours) funded by the Medical Research Council. He then completed his general medical training in London Hospitals. In 1997 he joined the North West Thames Rotation in Diabetes and Endocrinology as a Specialist Registrar. During this time he completed a PhD on the area of novel neuropeptides regulating appetite as a Wellcome Trust Clinical Training Fellow at Imperial College with Professor Sir Steve Bloom. In 2004 he was awarded a National Institute for Heath Research (NIHR) Clinician Scientist Fellowship and appointed Clinical Senior Lecturer & Consultant in Diabetes & Endocrinology at Imperial College London. Following this he was awarded an NIHR Career Development Fellowship and promoted to Reader in 2009. In 2011 he was promoted to Professor in Endocrinology & Metabolism. In 2015 Professor Dhillo was awarded a prestigious NIHR Research Professorship.
Professor Dhillo's research investigates novel aspects of endocrine control of obesity and reproductive function. His research has focused on understanding the neuroendocrine mechanisms which are important in the regulation of food intake. The regulation of body weight is complex and requires control of both food intake and energy expenditure. Gut hormones can powerfully reduce appetite and increase energy expenditure. Professor Dhillo's research investigates the mechanisms by which gut hormones mediate their effect. Recently he has shown that administration of gut hormones to human volunteers can alter neuronal activity in brain reward areas which control food intake (http://www.guardian.co.uk/science/2011/sep/11/obesity-food-appetite-suppressant). He was awarded the Royal College of Physicians Linacre Medal for this work. These findings have identified CNS pathways which have potential as novel targets for the development of anti-obesity drugs.
Professor Dhillo's recent translational research has identified the novel hormone kisspeptin as a potential novel therapy for infertility. Professor Dhillo has carried out the 'first time into human' studies of kisspeptin. He has shown that kisspeptin potently stimulates reproductive hormone release in human male and female volunteers. This work was awarded the American Endocrine Society Award for Excellence in Clinical Research and the British Society for Neuroscience Investigator Prize. Professor Dhillo has also shown that kisspeptin administration potently increased reproductive hormone release in women with infertility due to hypothalamic amenorrhea (http://www.bbc.co.uk/radio4/womanshour/04/2009_11_tue.shtml). Recently Professor Dhillo has shown for the first time in women with infertility that kisspeptin can be used safely and effectively in IVF treatment http://www.bbc.co.uk/news/uk-england-london-22953488. He was been awarded the Royal College of Physicians Goulstonian Lectureship (2010) and the Society for Endocrinology Medal (2015) for this work.
Professor Des Johnston
Professor Des Johnston trained in Edinburgh and Southampton where, as an MRC Training Fellow, he did his PhD with Professor George Alberti. His work at that time investigated metabolic disturbances in liver disease and metabolic aspects of endocrinology. He moved subsequently to Newcastle where he obtained a Wellcome Senior Clinical Research Fellowship, investigating metabolism in diabetes. In 1986, he was appointment to the Chair of Clinical Endocrinology at St Mary’s Hospital Medical School and the Royal Postgraduate Medical School, which became part of the Imperial College School of Medicine in 1996. He was appointed Dean (Clinical) of Imperial College London in 2004 and in 2006 he was appointed Campus Dean for the St Mary’s campus of Imperial College. His major interests currently are in the pathogenesis of type 2 diabetes. He is investigating early metabolic changes which are observed in people predisposed to develop type 2 diabetes, but before the onset of the disorder. The rationale of this approach is that such early changes may represent primary abnormalities which are causative. In July 2005, he was appointed Director of the UK Diabetes Research Network.
Professor Karim Meeran
Professor Meeran qualified from the Royal Free Hospital in 1988 and trained in Endocrinology at Hammersmith Hospital and St Bartholomew’s Hospital. He is Professor of Endocrinology, Deputy Director of Medical Education and Lead Clinician for Endocrinology. He has established a strong clinical and educational link with the Abu Dhabi Imperial College London Diabetes Centre. He has an international reputation for the treatment of Endocrine disease and has published extensively in this field.
Professor Meeran’s clinical focus is in all aspects of Endocrinology and Diabetes including thyroid, adrenal, hirsuitism, PCOS, prolactin and pituitary diseases, calcium and bone metabolism and neuroendocrine tumours. Professor Meeran's Private Services
Professor Graham WilliamsGraham Williams became Professor of Endocrinology at Imperial College London in 2005. He obtained a BSc in Anatomy and MBBS from St. Thomas’s Hospital, University of London and a PhD from the University of Birmingham. He trained as a Howard Hughes Medical Institute Fellow at Harvard Medical School, Boston, USA and as a Medical Research Council Training Fellow and Clinician Scientist Fellow at the University of Birmingham. He was appointed as Senior Lecturer at the Royal Postgraduate Medical School, London (1995) and received an MRC Career Establishment Award. He was promoted to Reader (2000) and subsequently Professor (2005) of Endocrinology.
Professor Williams is Head of the Molecular Endocrinology Laboratory in the Department of Medicine and MRC Clinical Sciences Centre at Hammersmith Campus. His research focuses on the molecular mechanisms of thyroid hormone action during skeletal development and in adult bone maintenance. This research is internationally recognised. Professor Williams receives regular invitations to speak at International Scientific Meetings all over the world and the laboratory collaborates widely throughout the UK, Europe and the USA as well as with groups in Japan and Singapore. Clinical Training Fellows, PhD students and post-doctoral scientists in the Molecular Endocrinology Group have received 24 prizes for research excellence in the last 10 years and Professor Williams has been awarded the Society for Endocrinology Medal in 2011 in recognition of his outstanding studies.
Professor Williams is currently the Treasurer of the Society for Endocrinology and serves as an Officer and Council Member. He is a member of the European Thyroid Association Executive Committee and a former Executive Committee Member of the British Thyroid Association.
Professor Williams is a current member of the Wellcome Trust Physiological Sciences Funding Committee and is a former member of the German Federal Ministry for Education and Research & E-Rare Group of National Research Funding Agencies Joint Transnational Call (E-RARE JTC 2009) Committee and Chairman of the Academy of Finland Research Council for Health Grant Committee (2007-2009). He has served on numerous Editorial Boards over the years and is currently an Editorial Board member of Endocrinology, Thyroid, Journal of NeuroEndocrinology, Expert Review of Endocrinology and Metabolism and Hot Thyroidology.
In addition to his research priorities, Professor Williams is Director of Education within the Department of Medicine and Head of Education for Clinical Programme Group 1 (Medicine) in the Academic Health Sciences Centre.
Prof Bassett is a Principal Investigator in the Molecular Endocrinology Group in the Department of Medicine and MRC Clinical Sciences Centre at the Hammersmith Hospital. His current research is focused on the molecular mechanism of thyroid hormone action. His particular interest is the role of thyroid hormone in skeletal development and the maintenance of adult bone. These studies have already clarified the complex relationship between central and peripheral thyroid status and identified a critical role for local thyroid hormone metabolism in bone. These studies are the result of longstanding and productive collaborations with many of the worlds leading thyroid hormone researchers.
The Molecular Endocrinology Group is an international leader in the field of thyroid hormone action and Dr Bassett frequently receives invitations to speak at International scientific conferences in Europe, America and Japan and his group has been awarded 9 research prizes in the last 7 years. Prof Bassett is currently a member of the Executive Committee of the British Thyroid Association and the British Thyroid Foundation Grant Committee. His is on the editorial board of the Journal of Endocrinology, Journal of Molecular Endocrinology and Thyroid Research. Prof Bassett is also involved in medical education at Imperial. He is member of the Graduate Entry MBBS committee and the course leader for Endocrinology.
Dr Amir Sam
Dr Amir Sam is a Consultant Endocrinologist at Hammersmith and Charing Cross Hospitals and a Reader at Imperial College London. He graduated from UCL with prizes and distinctions in all pre-clinical and clinical subjects. During his undergraduate training he received a scholarship to study Endocrinology at the Harvard Medical School. He completed his post-graduate medical training in Oxford and London. He completed his PhD in Neuroendocrinology as a Wellcome Trust Clinical Research Fellow at Imperial College London. He is the Head of Curriculum & Assessment Development and a member of the Imperial College School of Medicine Board. In 2015 he won the Imperial College President's Medal for Outstanding Contribution to Teaching Excellence as well as the Outstanding Teacher/Trainer of the Year Award from the Health Education North West London. Dr Sam's clinical focus is all aspects of endocrinology including pituitary, neuroendocrine, adrenal, thyroid, parathyroid, metabolic bone & reproductive disorders. He has written several textbooks including Lecture Notes in Endocrinology & Diabetes.
Professor Anne Dornhorst
Dr Tony Goldstone
He has researched and published widely on hormonal control of appetite, neuroendocrine, hypothalamic and metabolic abnormalities in obesity and the genetic Prader-Willi syndrome, particularly investigating the causes of hyperphagia, through pre-clinical, clinical, post-mortem, genetic, interventional, fat and brain imaging studies. This includes work as a research fellow at the Netherlands Institute for Brain Research in Amsterdam and the Division of Pediatric Genetics at the University of Florida, USA.
He is currently a Senior Clinician Scientist and Consultant Endocrinologist in the Metabolic and Molecular Imaging Group, MRC Clinical Sciences Centre, Hammersmith Hospital at Imperial College London. A major theme of his current work is using functional MRI and body fat MRI to investigate appetite, eating behaviour and obesity.
He is a Consultant Endocrinologist at Imperial College Healthcare NHS Trust with specialist adult and paediatric clinics for patients with Prader-Willi syndrome and genetic obesity, Endocrine dysfunction after traumatic brain injury, and gastroenteropancreatic tumours and familial Endocrine cancer syndromes, as well as in-patient work within Endocrinology, Diabetes and Acute Medicine.
Dr Emma Hatfield
Dr Emma Hatfield is a Consultant in Endocrinology and Diabetes, and General Internal Medicine, at Imperial College NHS Trust, and Honorary Senior Lecturer at Imperial College. She was appointed consultant in 2005 following clinical training in Cambridge and London. Her experience covers a broad range of Clinical Endocrinology. She has specific expertise in pituitary tumours, adrenal tumours, neuroendocrine tumours, thyroid disorders, bone and calcium metabolism and reproductive endocrinology.
Dr Niamh MartinDr Niamh Martin is a Clinical Senior Lecturer (Imperial College London) and Honorary Consultant in Diabetes and Endocrinology (Imperial College Healthcare NHS Trust) with a special interest in pituitary disease and neuroendocrine tumours.
Dr Martin gained a first class BSc in physiology and qualified with distinction from Liverpool University Medical School. She subsequently joined the North West Thames specialist registrar rotation in Diabetes and Endocrinology to pursue her interest in endocrine disease. During this period, she was awarded a Wellcome Trust Clinical Training Fellowship and undertook a PhD with Professor Steve Bloom at Imperial College London, focusing on the interaction between the hypothalamo-pituitary-thyroid axis and energy balance. She received the 2003 British Society for Endocrinology Novartis Young Endocrinologist Award for this work. In 2006, Dr Martin was awarded a National Institute for Health Research Senior Lectureship. Her research programme focuses on the diagnosis and treatment of neuroendocrine tumours and pituitary disease. In the Trust, Dr Martin chairs the Pituitary Multidisciplinary Team.
In addition to her clinical commitments and research programmes, Dr Martin is closely involved in undergraduate medical education at Imperial College medical school. She was awarded a Masters Certificate of Advanced Study in Learning and Teaching from Imperial College in 2008 and subsequently became a Fellow of the Higher Education Academy. As well as lecturing in undergraduate endocrinology, she is the Exam Board Chair for the second year undergraduate medical course.
Dr Harvinder Chahal BMedSci, MBBS, MRCP, PhD
Dr Harvinder Chahal is a Consultant in Endocrinology, Diabetes, Bariatric Medicine and General Internal Medicine at Imperial College Healthcare NHS Trust and Honorary Clinical Senior Lecturer at Imperial College, London. He qualified from St Bartholomew's and the Royal London School of Medicine in 2001. He trained in Endocrinology and Diabetes at St Bartholomew's Hospital. In 2007 he was awarded the prestigious Medical Research Council training fellowship to undertake research in the field of pituitary tumorigenesis, resulting in several influential research papers in high impact journals. He has been awarded several national and international prizes for his research and clinical work. He has written several textbook chapters. He is the member of the Society for Endocrinology and Diabetes UK. He is the Lead Bariatric Physician and manages patients prior to and after bariatric surgery and pharmacotherapy to reduce their complication risks and optimise the health benefits of weight loss. Dr Chahal is an experienced endocrinologist in all aspects of Endocrinology and Diabetes including thyroid, adrenal, prolactin and pituitary diseases, obesity, polycystic ovarian syndrome (PCOS), hirsutism, type 1 and type 2 diabetes and complications, parathyroid, calcium, vitamin D and bone metabolism, lipid disorders, hypertension, cardiovascular risk reduction and neuroendocrine tumours. Key published papers: http://www.researchgate.net/profile/Harvinder_Chahal2
He also has an interest in undergraduate medical education, and in 2016, he was appointed Director of Clinical Studies at Imperial College Healthcare NHS Trust (St Mary’s Hospital site).
Dr Chahal's Private Services
Dr Florian Wernig is a Consultant Endocrinologist at Imperial College Healthcare NHS Trust and a Honorary Clinical Senior Lecturer at Imperial College. He is experienced in all aspects of endocrinology with a particular interest in pituitary and adrenal disorders as well as neuroendocrine tumours and thyroid cancer. He graduated from the Leopold Franzens University of Innsbruck in Austria. Following an MD in molecular endocrinology at the Austrian Academy of Sciences and research at St George's University of London, he completed his postgraduate training in endocrinology and general internal medicine in London on the Imperial/Hammersmith rotation.
He practices at both Charing Cross and Hammersmith Hospitals.
Dr Wernig"s Private Services
Professor Nick OliverDr Nick Oliver qualified from St. Mary’s Hospital Medical School
in 1999 and trained in diabetes and endocrinology in London. He has active research in Imperial College with a special interest is diabetes technology, encompassing glucose monitoring technologies, insulin de
livery devices, closed loop insulin delivery and remote care to address cardiovascular risk and diabetes prevention. Dr Oliver was appointed as a Consultant and Honorary Senior Lecturer in 2010 and is lead clinician for diabetes technology and provides integrated community diabetes care.
Professor Tricia TanProf Tan is a Consultant in Endocrinology and Metabolic Medicine at Imperial College Health
care NHS Trust. She qualified in medicine at St Andrew's University and Manchester University in 1996. She completed her specialist training in Diabetes and Endocrinology at University College London, the Royal Free, Charing Cross and Hammersmith Hospitals. She possesses over 10 years’ experience in gut hormone research and physiological studies into the impact of gut hormones on weight and type 2 diabetes. She has completed several Phase I trials on the gut hormone analogues, which are being developed for the treatment of obesity. She is the director of the SAS Gut Hormone service, and her clinical research spans a wide gamut from the diagnosis and treatment of neuroendocrine tumours to diagnostic testing in Endocrine disorders. Her clinical interests are wide-ranging across all spheres of diabetes, endocrinology and metabolic medicine. Specific areas of interest are in obesity, neuroendocrine tumours, pituitary disease and analytical methods for measuring gut hormone levels.
Dr Jeannie Todd
Dr Todd is a very experienced endocrinologist, interested in all aspects of Endocrinology and Diabetes including thyroid, adrenal, PCOS, hirsuitism, prolactin and pituitary diseases, parathyroid disorders, calcium and bone meta
bolism and neuroendocrine tumours.
Dr Todd's Private Services
Professor Jonathan ValabhjiProf Jonathan Valabhji is a consultant physician based at St Mary’s Hospital. His specialist areas include Diabetes, Cardiovascular, General endocrinology, Lipid disorders, Diabetic foot, Insulin pumps, Thyroid disease, General internal medicine.
He attended medical school at Barts and The London School of Medicine and Dentistry, and qualified MBBS, BSc in 1990. He is currently the Diabetes Tsar for the UK.
He runs the 'World beating Diabetic Foot Service' at St Mary's Hospital.